How CBD Can Curb Chronic Inflammation

How CBD Can Curb Chronic Inflammation

Basic Jane |

Muscle pain and soreness are common challenges. Whether your sore muscles are a result of pushing yourself too hard at the gym, or due to an existing injury or chronic health condition, the pain and stiffness can make everyday activities difficult.
But now many are discovering something that can help: cannabidiol (CBD). Whether ingested or used as a topical, CBD can ease pain and inflammation for incredible results.
How Does CBD Help With Your Sore Muscles?
CBD is known for its ability to relieve pain and reduce inflammation, which can make a big difference when it comes to your sore muscles. It’s no wonder CBD edibles and topicals are increasing in popularity. Even celebrities like Kristen Bell swear by CBD’s incredible benefits for aches and pains.
So how can CBD help with your sore muscles? Folks say it helps them in a few different ways:
1. CBD relieves muscle pain: In general, CBD can help alleviate the pain from sore muscles. And it can reduce inflammation, which may help reduce the cause of the pain as well. Whether using an edible or applying a topical directly, people report big pain relief from CBD.
2. CBD eases strain on old injuries: Some who use CBD regularly say that it helps reduce the pain they experience from their old injuries. More research is needed to understand this phenomenon, but it may be related to both the pain-relieving properties of CBD and its ability to reduce inflammation at the injury site.
3. CBD reduces morning discomfort: Injuries and tension spots can both produce a lot of pain and stiffness in the morning. But when people use CBD the night before, they report less morning discomfort. Again, the inflammation reduction may be largely responsible for helping reduce pain even after the pain-relieving effects of the CBD wear off.
4. CBD relieves post-workout soreness: Feeling sore after an intense workout at the gym? Many swear by CBD as a way to relieve post-exercise soreness. This can help with workout recovery, so you don’t have to wait forever to get back to your exercise routine.
The Science Behind CBD’s Ability to Relieve Sore Muscles
So how does CBD pull off its pain-relieving powers?
It all has to do with how CBD interacts with the endocannabinoid system (ECS). This crucial system of neurotransmitters is found all over the body and controls or effects some of its most important functions, such as:

  • Hunger
  • Pain
  • Stress response
  • Memory building
  • Inflammation
  • Sleep
  • Muscle control
  • Energy
  • Mood

The ECS both produces and is activated by the body’s natural endocannabinoids. But plant cannabinoids, the medicinally potent chemicals in cannabis, activate the ECS, too. CBD interacts with these receptors to ease pain and inflammation, among other benefits.
When you eat CBD, it’s processed through the digestive system and enters the bloodstream, which allows it to affect the entire body. With topicals, however, CBD must permeate the skin, activating the ECS’s CB2 receptors where it’s been applied. This allows for local pain and inflammation reduction, exactly where the patient applies the CBD.
Whether you use it topically or ingest it, CBD won’t get you high the way tetrahydrocannabinol (THC) does, another reason people have started turning to the cannabinoid more and more.
Still, when it comes to topical CBD, there’s a debate about how much the skin can actually absorb CBD, and whether it makes it to the muscles at all. While it’s unlikely that CBD makes it to the muscles directly, there’s a phenomenon that happens with heating or cooling cream, which may be at play with CBD as well.
Basically, the sensation (such as heat, cool or in CBD’s case pain relief) on the skin desensitizes the nerves to the muscle pain below by distracting them with stimuli on top. This may be how CBD topicals help with pain that’s more than skin deep.
Treating Your Sore Muscles With CBD
To learn more about using CBD for sore muscles, we spoke with Jessica Tonani and Kersten Beyer, the founders of Basic Jane, the only cannabis company in the U.S. with a license to research CBD. Their product line of hemp-derived CBD topicals was specifically designed to help people with everyday aches and pains.
Their research looked at the efficacy of products with CBD, THC or a combination, and found that CBD seems to be effective in treating sore muscles. In fact, they even found that in topical form, CBD works as well for pain as THC-based products do.
So, if both topicals and edibles are effective for treating sore muscles, which should you use? It really depends on what you need it for. “We tell people it’s kind of like the difference between using an Aspercreme or an Advil,” says Jessica. “The edible is more of a full body effect and not as localized and may be not as strong as if localized, but it has a tendency to work everywhere; whereas a topical will really only work where you put it.”
If you have a sore muscle in one location, such as knee pain, a topical is probably your best bet. But as Jessica points out, “If you have knee pain, hip pain, finger pain, something like that, then you’re going to have to use topicals on multiple locations, and maybe something more systemic may be better for you.”
Another consideration is the topical you’re using. There are so many different types of CBD topicals, but they aren’t all equally effective. “Your skin is a really good barrier. It’s designed to protect you and keep things from getting into your body,” says Jessica, explaining that CBD needs something called a carrier molecule to help it permeate the skin.
Menthol and alcohol are two options that can help CBD penetrate the skin, and Basic Jane makes sure they have carrier molecules in their products. “We have a cream that’s heavy on the menthol, which is also a pain reliever,” says Kersten.
Want to treat your sore muscles with CBD? Look for edible CBD like:

  • Tinctures
  • Capsules or infused treats

For localized pain, go for a topical CBD with a good carrier molecule. Then just wait for the pain and inflammation to melt away.

Frequently Asked Questions

Oral CBD Products

What makes Basic Jane oral products different from other CBD edibles?

Basic Jane oral products are developed out of one of the first state-licensed cannabis research programs in the U.S. Every formula is designed by scientists with a focus on real-world use, consistent dosing, and meaningful results. All oral products are THC-free — so you get the benefits of cannabinoids without any psychoactive effects or concerns about drug testing.

Do Basic Jane oral products contain THC?

No. All Basic Jane oral products are 100% THC-free and are legally sold under the 2018 Farm Bill. They will not get you high and are designed for clear-headed, everyday wellness.

Which oral product is best for general pain and inflammation relief?

It depends on what you need! CBD Mints are a great everyday starting point — low-dose, gentle, and appropriate for any time of day. For stronger inflammation relief, Boost Mints contain both CBD and CBDA (the raw form of CBD), which provides an added boost for more significant discomfort. Both work systemically, meaning they support your whole body — not just one area.

What is the difference between CBD Mints and Boost Mints?

CBD Mints contain 5 mg of CBD per mint — a perfect microdose for consistent, all-day support. Boost Mints contain both CBD and CBDA for extra inflammation relief. Think of CBD Mints as your everyday companion and Boost Mints as your go-to when you need more firepower — particularly after a tough workout, a flare-up, or a harder day.

What are Refresh Chews best for?

Refresh Chews contain CBD, CBG, and terpenes, making them ideal for people who want to power through their day with more clarity and ease. They are designed to help reduce anxiety, support focus and energy, and keep you feeling your best without any jittery side effects. Perfect for busy mornings or an afternoon pick-me-up.

What are Passion Chews and who are they designed for?

Passion Chews are designed specifically for women — particularly post-menopausal women — to help them feel present, connected, and in the moment when they want to. They are thoughtfully formulated with women's hormonal health in mind and designed to support intimacy and overall well-being.

What are Night Caps and are they CBD?

Night Caps are actually cannabinoid-free. Instead, they contain a blend of hops (Humulus lupulus) and valerian (Valeriana officinalis) — two botanicals with a long history of traditional use as natural sleep aids. They are non-habit-forming and designed to help you wind down, fall asleep, and wake up refreshed. A wonderful option for anyone who prefers to keep their sleep routine free of cannabinoids.

Which oral product is best for sleep?

Night Caps are Basic Jane's dedicated sleep product and are the first recommendation for anyone struggling to get a good night's rest. Their blend of hops and valerian is non-habit-forming and designed specifically for sleep support. If you are also managing pain that interferes with sleep, pairing Night Caps with a CBD Mint or Boost Mint may provide broader comfort going into bedtime.

Which oral product is best for daytime use?

CBD Mints are perfect for any time of day — subtle, low-dose, and easy to take on the go. Refresh Chews are a standout daytime choice if you want an added edge: the CBD/CBG and terpene blend is designed to keep anxiety at bay and help you feel energized and focused. Both are discreet, minty, and easy to incorporate into your daily routine.

Which oral product is best for workout recovery?

Boost Mints are a great post-workout choice. The combination of CBD and CBDA works systemically throughout the body to support inflammation relief and recovery. Take one to two mints after exercise and give them 30–90 minutes to build. For faster, localized muscle relief right after a workout, consider pairing with a Relieve Cream or Relieve Gel topically as well.

Can I use oral and topical products together?

Yes — and many customers do. Topicals like the Relieve Cream, Relieve Gel, and Pain Sprays target localized areas like sore knees, shoulders, or back, while oral products like CBD Mints and Boost Mints provide systemic, whole-body support. Using both together is one of the most effective approaches for people managing chronic or widespread discomfort.

How Oral CBD Works

How is oral CBD different from topical CBD?

Topical CBD products work locally — you apply them directly to the area of discomfort and they interact with receptors in the skin and underlying tissue. Oral products are absorbed through digestion and work systemically, supporting your whole body rather than one specific area. This makes oral products especially valuable for conditions that are more widespread, internal, or mood- and sleep-related.

How long does it take for oral CBD products to work?

Oral products typically take 30–90 minutes to take effect, depending on your metabolism and whether you have eaten recently. Plan accordingly — they are not a rapid-response product in the way topicals are, but their effects last significantly longer.

How long do the effects of oral CBD last?

Effects from oral CBD products typically last 6–8 hours, making them a great choice for consistent, long-lasting support throughout the day or night.

What is CBDA and why is it in Boost Mints?

CBDA is the raw, unheated form of CBD found in the hemp plant. Research suggests it may have potent anti-inflammatory properties, and when combined with CBD, the two cannabinoids may work synergistically for enhanced effect. That is why Boost Mints contain both — to deliver extra support beyond what CBD alone can provide.

What is CBG and why is it in Refresh Chews?

CBG (cannabigerol) is sometimes called the "mother cannabinoid" because it is the precursor to other cannabinoids. It is being studied for its potential to support mood, energy, and focus. In Refresh Chews, CBG is combined with CBD and terpenes to create a formula specifically designed to help you feel clear-headed, calm, and energized.

Activity and Timing

When is the best time to take CBD Mints?

CBD Mints are designed for any time of day. Many customers take one in the morning as part of their wellness routine, another mid-afternoon, or after activity for recovery. Because each mint is a low 5 mg dose, you can adjust timing and quantity to fit your lifestyle. Start with one and see how your body responds.

When is the best time to take Boost Mints?

Boost Mints are best taken when you need more targeted inflammation support — after exercise, during a flare-up, or when you know a more demanding day is ahead. Because they contain both CBD and CBDA, they are more potent than standard CBD Mints and are ideal when everyday support is not quite enough.

When should I take Night Caps?

Take Night Caps about 30–60 minutes before bed to give the hops and valerian time to take effect. They are designed to help you relax, fall asleep naturally, and stay asleep through the night.